However, they also found that tweaking some genes in fruit flies prevented the build-up of F-actin and extended the flies’ healthy lifespan by around 30%. “Flies get more forgetful as they age ...
Visualization of filamentous actin (F-actin) in living cells is critical for the study of morphogenetic processes such as cell division, migration or polarization. We recently described in these ...
“In fact, aging is associated with not only changes in the expression of actin genes but also disruption of actin cytoskeletal dynamics. However, they pointed out, the interplay between actin ...
Drosophila melanogaster, or fruit flies, are convenient research tools, and they have many genes in common with humans. | ...
Last year, the UB team published a study showing that the active form of the CHRFAM7A gene allows brain cells to be more ...
The gene tweaking only targeted neurons ... This discovery suggests that the build-up of F-actin could be a driver for age-related cognitive decline, and researching it further could help us ...
By tweaking a few specific genes in aging fruit flies' neurons, the researchers prevented F-actin buildup, maintained ...