Although the Cvt pathway is the only known biosynthetic use of autophagy, selectivity represents an important aspect of many autophagic processes. For example, specific organelle degradation has ...
Ketone bodies, known for their role in energy metabolism during fasting, have been shown to directly interact with damaged ...
The Overholtzer lab studies mechanisms of nutrient sensing and cellular responses to nutrient starvation, including the nutrient recycling pathway autophagy, scavenging pathways such as ...
Autophagy is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Japanese ...
The Overholtzer lab studies mechanisms of nutrient sensing and cellular responses to nutrient starvation, including the nutrient recycling pathway autophagy, scavenging pathways such as ...
This means that the cells found new ways to survive the drug without relying on the expected autophagy pathway. The study ...
Furthermore, they found that downregulation of BAG3, a protein involved in protein clearance through the autophagy-lysosome pathway, contributes to the accumulation of hyperphosphorylated tau in ...
Diabetes drug development gets an advance in study that shows Inceptor binds excess insulin within the beta cell and directs it towards degradation.