as the features exhibited by internalized cells are reminiscent of 'cell-in-cell' or cell 'cannibalism' images observed in metastatic cells. They discovered that cells from both classes of tumours ...
Among the cell death mechanisms addressed are: pro-apoptotic signals resulting from activation of the ER-associated kinase IRE1, an upstream activator of apoptotic signalling kinase 1 (ASK1 ...
Professor Meier and his group are studying the complex relationship between cell death, inflammation and adaptive immunity, and how this knowledge might be applied to deliver better anti-cancer drugs ...