This paper presents the important discovery that lipid metabolic imbalance caused by Snail, an EMT-related transcription factor, contributes to the acquisition of chemoresistance in cancer cells.

Researchers have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects. By applying brief, localized pulses of magnetic fields, the team ...

在肺癌治疗的领域，非小细胞肺癌（NSCLC）患者对免疫检查点阻断（ICB）疗法的耐药性一直是一个棘手的问题。近日，同济大学张鹏教授及其团队在《Nature Genetics》上发表了一项引人注目的研究，名为“Multi-omic profiling highlights factors associated with resistance to immuno-chemotherapy in non ...

The research gives insight into the function of immune cells in patients with chemotherapy-resistant breast cancers. While chemotherapy may not kill cancer cells in these high-risk patients, ...

Brief, localised pulses of magnetic fields have been found to increase the uptake of chemotherapy drug doxorubicin.

In these drug-resistant cancer cells ... mismatch repair deficiency and temozolomide chemotherapy, Nucleic Acids Research (2024). DOI: 10.1093/nar/gkae1122 ...

A new study from Cedars-Sinai Cancer reveals a potential way to overcome tumor resistance to a common chemotherapy drug ...

Mar. 14, 2022 — A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores ...

Future Oncol. 2012;8(9):1135-1147. Combination chemotherapy in platinum-resistant ovarian cancer eventually fails to improve overall survival but increases toxicity. The CARTAXHY trial performed ...