With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

Pericentromeric heterochromatin flanks centromeric chromatin, and contains a high density of cohesin, which mediates sister-chromatid cohesion. (B) Schematic depiction of centromeric DNA in humans ...

Replicated chromosomes remain attached to each other by their central region: the centromere. As long as they remain attached to each other the two identical copies of the chromosome are known as ...