Now, researchers at the University of Alabama at Birmingham (AL, USA) have used single-cell analysis to better understand how ...

University of Alabama researchers reveal a key mechanism in BK polyomavirus replication, challenging existing models. The ...

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...

Market OverviewDNA polymerases catalyze the synthesis of DNA molecules from nucleoside triphosphates, ensuring the accurate ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV.

Each time they need to copy both their DNA and the structure in which the DNA is packed. This packaging, called chromatin , acts as a guide. It tells the cell how, where and when to 'read' and use ...

The reliability of the DNA replication process depends on genome stability, which is maintained by DNA repair mechanisms that correct any mistakes that occur during DNA replication. Failures in ...

The reliability of the DNA replication process depends on genome stability, which is maintained by DNA repair mechanisms that correct any mistakes that occur during DNA replication. Failures in these ...

The study is published in the journal PLOS Pathogens. With only seven genes, the BK polyomavirus must use the host cell’s DNA replication machinery to produce new viruses. Although the virus was ...

Researchers reveal new findings on BK polyomavirus replication, offering potential drug targets to protect kidney transplants.

The reliability of the DNA replication process depends on genome stability, which is maintained by DNA repair mechanisms that correct any mistakes that occur during DNA replication. Failures in ...

However, accidents can occur, for example due to radiation or errors during DNA replication ... high-fidelity repair pathway ...