Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

Because Mediator interacts with both DNA-binding TFs and the general transcription machinery (including pol II), Mediator acts as a molecular bridge to link these factors and facilitate TF-dependent ...

Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA -- that molecular blueprint for life -- ...

In genetics, it has generally been accepted that each gene has one transcription initiation site, located downstream of a ...

New research has filled in gaps in the original soybean reference genome, identifying thousands of transcription initiation ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

Generally, they were not, as the proteins targeted promoter regions of DNA and the three prime untranslated ... polyadenylation and altering mRNA after transcription via enzymes through a process ...