To determine the TCR signalling capacity of the CD3ɛ mutant T cells, the authors measured the levels of extracellular signal-regulated kinase (ERK) phosphorylation and CD69 expression.

Cui et al. 3 also used contextual fear conditioning to confirm the correlation between learning and increased phosphorylation of ERK and synapsin1. This model provided an additional assessment of ...

In conclusion, by identifying PEBP1 as an amplifier of mitochondrial stress signals, our study provides new insights into cytoplasmic mechanisms which ensure appropriate responses to acute ...