Enzyme activation typically happens when small molecules bind outside the active site, to increase the enzyme’s activity ... But if we want to do frontier science, then we need to think outside ...

This led to the discovery that to achieve the activity they were pursuing, the enzyme would need to first undergo a specific chemical modification. In fact, this modification should have been ...

leading to an increase in enzyme activity. This means the active site loses its important shape and can no longer form enzyme-substrate complexes, leading to a decrease in enzyme activity.

Because enzymes are not part of the product, they can be reused again and again. How efficient! Enzyme activity measures how fast an enzyme can change a substrate into a product. Changes in ...

The research extends the functional capabilities of nanozymes, shifting the focus from small molecule substrates to complex ...

While the activity of a few RNA enzymes -- called ribozymes -- have ... biochemistry and molecular biology in the Eberly College of Science at Penn State and the leader of the research team.