A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that ...

A team of scientists led by Professor Annette Beck-Sickinger from the Institute of Biochemistry at Leipzig University has ...

A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists ...

G protein coupled receptors (GPCRs) are the most abundant receptor family encoded by the human genome. They are involved in all aspects of mammalian cellular life, and are extraordinarily diverse both ...

GPR6, a G protein-coupled receptor, is primarily expressed in the medium spiny neurons of the striatum, specifically within ...

HETE is the endogenous agonist for G protein-coupled receptor 39 (GPR39) in vascular smooth cells, so researchers ...

A cell’s ability to react to its surroundings is one of its fundamental roles. Therefore, it makes sense that one of the ...

A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists ...

Researchers have identified a natural substance, hederagenin, that blocks the NPFFR1 receptor, a protein involved in pain perception in the brain and spinal cord.

Kokumi refers to the enhanced and more delicious state of food flavor. However, the underlying neuroscientific mechanisms remain largely unexplored. Our previous research demonstrated that ornithine ...

Septerna Inc. has divulged compounds acting as mas-related G-protein coupled receptor member X2 (MRGPRX2) antagonists reported to be useful for the treatment of asthma, cancer, multiple sclerosis, ...