The hedgehog (Hh) signaling pathway regulates the differentiation and growth of numerous cell types, including chondrocytes, and thus is essential for normal skeletal development. Pharmacological ...

The Hedgehog (Hh) pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. The first and often genetically ...

pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems and play a role in BCC. The requirement ...

The scientific team focused its investigations on the GP130 signaling pathway, which researchers expect to have a major potential in the fight against cancer. The signaling pathway, which is ...