Molecular chaperones have long been heralded as machines for folding and salvaging proteins ... degradation of substrates bound to heat-shock protein 70 (Hsp70) and/or Hsp90.

Heat Shock Protein 90 (Hsp90), which has spanned the research pathway from bench to bedside. Hsp90 caught the eye of ICR scientists in the 1990s. At the time there was little support for Hsp90 as a ...

These proteins, which include enzymes that do specialized jobs, control the activities of the cell. Different cells have different activities. By controlling protein synthesis within each cell ...

Hereditary spastic paraplegia, or HSP, is a group of movement disorders ... which typically facilitates the transportation of proteins within nerve cells called neurons. When that function is ...