Large swings in international normalized ratio should be avoided during initiation of warfarin (especially in patients at risk of WISN and in those not receiving heparin). Finally, early diagnosis ...

Clinically significant bleeding occurred in 10 patients who received heparin versus 7 who did not (9% vs 0.6%). To conclude, an interruption of warfarin therapy for <6 days carries a low risk of ...

Purpose: A case of heparin-induced thrombocytopenia (HIT) complicated by warfarin-induced skin necrosis (WISN) is reported. Summary: A patient with a history of hypertension, heart failure ...