Because enzymes are little molecular machines, heat cycling is enough to get them to do the work of DNA replication. The ...

A graphical representation of how cis-regulatory elements work to turn genes on or off and open possibilities for personalized medicine. Disclaimer: AAAS and EurekAlert! are not responsible for ...

A woman expecting her first child got thinking about DNA, and sparked major debate with one simple question. Brianna Donovan, 28 and from Boston, Massachusetts, took to her TikTok account @brianna ...

University of Alabama researchers reveal a key mechanism in BK polyomavirus replication, challenging existing models. The ...

Recent work has clarified how higher eukaryotic cells 'licence' DNA replication precisely once per cycle. An inhibitor, geminin, prevents replication before mitosis by inhibiting the replication ...

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV.

By uncovering how certain DNA structures drive replication stress, this work contributes to a better understanding of how cancer develops. It may also open the door to new treatment approaches that ...

Researchers reveal new findings on BK polyomavirus replication, offering potential drug targets to protect kidney transplants.

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...