Because enzymes are little molecular machines, heat cycling is enough to get them to do the work of DNA replication. The ...

A graphical representation of how cis-regulatory elements work to turn genes on or off and open possibilities for personalized medicine. Disclaimer: AAAS and EurekAlert! are not responsible for ...

Recent work has clarified how higher eukaryotic cells 'licence' DNA replication precisely once per cycle. An inhibitor, geminin, prevents replication before mitosis by inhibiting the replication ...

By uncovering how certain DNA structures drive replication stress, this work contributes to a better understanding of how cancer develops. It may also open the door to new treatment approaches that ...

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...

Now that scientists have used the system to understand the role of telomeres in budding yeast DNA replication, they now hope to develop this insight to understand how telomeres work in human cells. Dr ...

University of Alabama researchers reveal a key mechanism in BK polyomavirus replication, challenging existing models. The ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research at the University of Alabama at Birmingham reveals new aspects of BKPyV ...

Researchers reveal new findings on BK polyomavirus replication, offering potential drug targets to protect kidney transplants.

With only seven genes, the BK polyomavirus must use the host cell’s DNA replication machinery to produce new viruses. Although the virus was discovered over 50 years ago, little is known about how ...