IgA 肾病的「四重打击」病理机制学说被广泛认可。基于此,近年来 IgA 肾病新药研发有了较大突破,涌现出不少靶向治疗药物,IgA 肾病或将迈入靶向治疗时代。
Immunoglobulin A (IgA) nephropathy, aka Berger disease, is a rare autoimmune disease that affects your kidneys. Though rare, IgA nephropathy (IgAN) is one of the leading causes of kidney failure.
糖皮质激素:在经过90天的优化支持治疗后,如尿蛋白仍高于1g/24h,则应考虑对高风险患者为期6个月的糖皮质激素治疗。副作用:向心性肥胖、骨质疏松、免疫力下降、血糖升高、消化道溃疡、电解质紊乱等。
IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells. Kidney Int. 67 , 504–513 (2005). Article CAS PubMed Google Scholar ...
Immunosuppressive therapy is effective against IgA nephropathy, but is not always suitable because of serious adverse effects. Magistroni et al. retrospectively reviewed 237 IgA nephropathy cases ...
The kidneys act as a filtering system in the human body that help in the removal of excess fluids and unwanted wastes from ...
Credit: Thinkstock Investigators attending ASN’s Kidney Week 2024 reported progress on a number of IgA nephropathy drug trials. IgA nephropathy trials of new and emerging therapies that target B ...
SAN DIEGO -- A novel drug significantly reduced IgA nephropathy-related proteinuria, according to interim findings of the ...
The global IgA Nephropathy Disease Treatment Market is at the forefront of addressing the growing burden of renal diseases worldwide. With a projected value surpassing USD 485 million by 2028, the ...
Renalys Pharma’s sparsentan receives Japanese Orphan Drug Designation for primary IgA nephropathy: Tokyo, Japan Tuesday, December 3, 2024, 11:00 Hrs [IST] Renalys Pharma, Inc., ...
Doncaster and Bassetlaw Teaching Hospitals (DBTH) has become the first site in Europe to enrol patients in a revolutionary clinical study evaluating the efficacy and safety of Ravulizumab, a potential ...