IgA 肾病的「四重打击」病理机制学说被广泛认可。基于此,近年来 IgA 肾病新药研发有了较大突破,涌现出不少靶向治疗药物,IgA 肾病或将迈入靶向治疗时代。
Immunoglobulin A (IgA) nephropathy, aka Berger disease, is a rare autoimmune disease that affects your kidneys. Though rare, IgA nephropathy (IgAN) is one of the leading causes of kidney failure.
Immunosuppressive therapy is effective against IgA nephropathy, but is not always suitable because of serious adverse effects. Magistroni et al. retrospectively reviewed 237 IgA nephropathy cases ...
et al. Baseline Characteristics and Associations of Using SGLT2 Inhibitors in IgA Nephropathy in China: Results from the CPO-IGAN. ASN 2024, FR-PO861. 3.KDIGO 2024 Clinical Practice Guideline for ...
IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells. Kidney Int. 67 , 504–513 (2005). Article CAS PubMed Google Scholar ...
IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their ...
IgA nephropathy is the most common primary glomerulonephritis and contributes to kidney failure. Growing evidence exists that the overactivation of the lectin pathway contributes to the pathogenesis ...
The kidneys act as a filtering system in the human body that help in the removal of excess fluids and unwanted wastes from ...
The global IgA Nephropathy Disease Treatment Market is at the forefront of addressing the growing burden of renal diseases worldwide. With a projected value surpassing USD 485 million by 2028, the ...
SAN DIEGO -- A novel drug significantly reduced IgA nephropathy-related proteinuria, according to interim findings of the ...
Renalys Pharma’s sparsentan receives Japanese Orphan Drug Designation for primary IgA nephropathy: Tokyo, Japan Tuesday, December 3, 2024, 11:00 Hrs [IST] Renalys Pharma, Inc., ...
Doncaster and Bassetlaw Teaching Hospitals (DBTH) has become the first site in Europe to enrol patients in a revolutionary clinical study evaluating the efficacy and safety of Ravulizumab, a potential ...