One of these original strands is called the leading strand, whereas the other is called the lagging strand. The leading strand is synthesized continuously, as shown in Figure 5. In contrast ...

This distinction represents a key difference between the functions of the leading strand clamp loader (CTF18-RFC) and the lagging strand clamp loader (RFC) and illuminates an important aspect of ...

One moves continuously to produce the new daughter DNA molecule on the leading strand, whereas the other produces a long series of short Okazaki DNA fragments on the lagging strand. Both ...