By these criteria, ISS have little direct effect upon either CD4 + or CD8 + T ... results in two T-cell phenotypes: antigen-specific cytotoxic lymphocyte (CTL) activity and a T h 1-biased immune ...

the method described here provides a novel way to obtain polyclonal tumor-reactive T-cell populations by their effector function without knowledge of the tumor antigen and without excluding CD4 ...

The CD4 count is a test that measures how many CD4 cells you have in your blood. These are a type of white blood cell, called T cells, that move throughout your body to find and destroy bacteria ...

Attributes such as a balanced CD4/CD8 ratio, enriched memory phenotypes ... exemplify the critical role of translational research in advancing cancer care. T cell receptor repertoire characteristics ...