Along with Aβ plaques, the second key pathology identified was neurofibrillary tangles (NFTs). Since the discovery of these two factors, our understanding of AD pathophysiology has continued to grow.

Amyloid-β (Aβ)-rich plaques and tau-containing neurofibrillary tangles are neuropathological hallmarks of Alzheimer's disease (AD). Currently approved drugs for AD target cholinesterase ...

Despite decades of starts and stops, new treatments and key genetic discoveries are giving researchers great hope for slowing or eventually preventing Alzheimer’s disease.

The brain cells, or neurons, also showed signs of recovery, the scientists reported in Nature Neuroscience. This discovery ...

Using genetic tools, the scientists then blocked TYK2 in the mice with Alzheimer's. This resulted in a reduction in the ...

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