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AIMS: To compare the glycaemic control of an insulin lispro mixture (25% insulin lispro and 75% NPL) twice daily in combination with metformin to that of once-daily insulin glargine plus metformin ...

rapid-acting insulin aspart, and premix insulin preparations including the combination of insulin degludec and aspart. To improve the convenience of our medicines, we introduced the world’s ...

Other criteria included a baseline HbA1c between 7% and 12% for those using basal insulin only and 12% or less for those using basal and bolus or pre-mixed insulin. Secondary objectives included ...