CRT contains a cleavable signal sequence in this domain, which is found in proteins that are marked for targeting to the ER, and the presence of this signal indicates that CRT is transported into ...

The technological demand for bioconjugate chemistry is fueled by the exponential growth of pharma and biopharma. The protein targeting chemistry comprises varying aspects, including precision protein ...

We have identified the IRE1/XBP1 branch of the Unfolded Protein Response (UPR) or endoplasmic reticulum (EnR) stress response as a previously unexplored therapeutic vulnerability in MYC-driven breast ...

Salicylic acid is vital for protecting plants from pathogens, but its synthesis remains unclear. A recent study by Shinshu ...

This approach not only represents a significant advance in targeting transcription factors and disordered proteins, but also showcases the PLP technology's versatility and potential to ...

Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...

Arvinas, Inc. (Nasdaq: ARVN) today announced that three posters for vepdegestrant, including clinical data, will be presented ...