The T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells essential for the survival, affinity maturation, and class switch recombination of B cells. They promote effective B-cell ...

They promote successful B-cell antibody-mediated immune responses. The dysregulation of Tfh cells is linked to chronic graft-versus-host-disease and autoimmune disorder systemic sclerosis.

B cells, components of the body's immune system, produce antibodies to combat pathogens such as viruses that enter the body from the outside. T follicular helper (TFH) cells assist B cells in ...

Kinetic analyses revealed that influenza nucleoprotein (NP)-specific BRMs differentiated early after infection and required T follicular helper (Tfh) cell help. BRM differentiation coincided with ...