Antifungal development is inherently difficult ... The early 2000s saw the development of the second-generation triazole, voriconazole, which, due to its efficacy and comparatively low toxicity ...

Standard treatment is to give what are known as the triazole class of antifungal drugs. However, there has been a significant worldwide increase in resistance to these medicines. “Early and accurate ...

[69] The presence of triazole-resistant mutations is therefore often difficult to predict. In addition, even selected antifungal susceptibility testing for mucosal isolates is costly and not ...

Voriconazole Triazole Inhibits ergosterol synthesis ... Corticosteroids used in the absence of an efficacious antifungal agent may aggravate fungal invasion by suppressing the immune response.