A prospective, randomized, controlled clinical trial compared metronidazole 250 mg orally four times daily with vancomycin 500 mg orally four times daily, each for 10-day courses. [43] Fewer ...

Treatment for an initial episode and a first recurrence of CDI: If oral therapy is possible: Nonsevere: metronidazole 500 mg three-times daily (t.i.d.) orally for 10 days; Severe: vancomycin 125 ...