S-palmitoylation is a PTM catalyzed by zinc finger DHHC domain containing (zDHHC) acyltransferases that affects both localization and activity of proteins regulating synaptic plasticity and ...

Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, they can counteract the cognitive decline and brain damage typical of the ...