The hedgehog (Hh) signaling pathway regulates the differentiation and growth of numerous cell types, including chondrocytes, and thus is essential for normal skeletal development. Pharmacological ...

pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems and play a role in BCC. The requirement ...

The scientific team focused its investigations on the GP130 signaling pathway, which researchers expect to have a major potential in the fight against cancer. The signaling pathway, which is ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal stem cell growth and tumorigenesis. The evidence supporting the ...

Stress hormones, not impaired insulin signaling, may underlie obesity-related diabetes, according to Rutgers research.

Depletion of eIF3d or eIF3e, but not eIF3h reduced the levels of multiple components of the MAPK signaling pathways. Surprisingly, however, depletion of all three eIF3 subunits increased MAPK/ERK ...

Early interventions in autism screening could be enhanced by focusing on the microbiome, which shows promise in identifying ...