Lipid-polymer nanoparticles to probe the native-like ... - Nature
2024年8月30日 — Polymers can facilitate detergent-free extraction of membrane proteins into nanodiscs (e.g., SMALPs, DIBMALPs), incorporating both integral membrane proteins as well …
Passive, active and endogenous organ-targeted lipid and polymer ...
2023年1月19日 — Lipid and polymer nanoparticles represent leading approaches for the clinical translation of genetic drugs. These systems circumnavigate biological barriers and facilitate …
Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview …
2023年8月21日 — In this review, we introduce the main types of LNPs used in drug formulations such as liposomes, nanoemulsions, solid lipid nanoparticles, nanostructured lipid carriers, and …
Polymeric Lipid Hybrid Nanoparticles (PLNs) as Emerging Drug …
Polymeric lipid hybrid nanoparticles (PLNs) are core–shell nanoparticles made up of a polymeric kernel and lipid/lipid–PEG shells that have the physical stability and biocompatibility of both …
Lipid nanoparticles for mRNA delivery | Nature Reviews Materials
2021年8月10日 — In this Review, we briefly overview representative lipid nanoparticles used for mRNA delivery and describe key steps in the preclinical development of lipid …
Lipid-polymer hybrid nanoparticles: Synthesis strategies and biomedical ...
2019年5月1日 — This review article is an updated overview on lipid-polymer hybrid nanoparticles (LPHNs) including the various types of LPHNs polymers used in their preparation, various …
Lipid Nanoparticles─From Liposomes to mRNA Vaccine Delivery, …
2021年6月28日 — Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital …
Lipid–polymer hybrid nanoparticles as a new generation …
2013年11月1日 — Lipid–polymer hybrid nanoparticles (LPNs) are core–shell nanoparticle structures comprising polymer cores and lipid/lipid–PEG shells, which exhibit complementary …
Lipid–polymer hybrid nanoparticles as a next-generation drug …
Lipid–polymer hybrid nanoparticles (LPHNPs) are next-generation core–shell nanostructures, conceptually derived from both liposome and polymeric nanoparticles (NPs), where a polymer …
Lipid–Polymer Hybrid Nanosystems: A Rational Fusion for ... - MDPI
2023年8月23日 — To overcome these limitations of PNPs and lipid nanoparticles, a new system called lipid–polymer hybrid nanoparticles (LPHNPs) has been developed owing to the …