Methotrexate: Uses, Dosage, Side Effects, Warnings - Drugs.com
2024年10月31日 · Methotrexate can cause serious or fatal side effects. Tell your doctor if you have diarrhea , mouth sores, cough, shortness of breath, upper stomach pain, dark urine, numbness or tingling, muscle weakness, confusion, seizure, or skin rash that spreads and causes blistering and peeling.
Methotrexate: 7 things you should know - Drugs.com
2024年11月15日 · Methotrexate usually shows some benefit in psoriasis within six to eight weeks; however, full effects may not be seen for five to six months. In chronic plaque psoriasis, 50-70% report a good result. When given to treat cancer, the length of time for an effect depends on the type of cancer and the patient's response to methotrexate.
Methotrexate Side Effects: Common, Severe, Long Term - Drugs.com
2024年2月23日 · Withhold or discontinue methotrexate oral solution as appropriate. Oral route (tablet) Embryo-Fetal Toxicity Hypersensitivity Reactions, and Severe Adverse Reactions. Methotrexate tablets can cause embryo-fetal toxicity, including fetal death. For non-neoplastic diseases, Methotrexate tablets are contraindicated in pregnancy.
Methotrexate injection Uses, Side Effects & Warnings - Drugs.com
2023年5月8日 · Methotrexate injection can cause serious or fatal side effects. Tell your doctor if you have diarrhea, mouth sores, shortness of breath , upper stomach pain, dark urine, numbness or tingling, muscle weakness, confusion, seizures, or skin …
Methotrexate Dosage Guide + Max Dose, Adjustments - Drugs.com
2023年5月8日 · Monitor methotrexate concentrations at least daily and make adjustments to hydration and leucovorin dosage as necessary. In cases where patients have toxic plasma methotrexate concentrations (greater than 1 micromole per liter) and delayed methotrexate clearance due to impaired renal function, glucarpidase should be administered. Patient advice:
Methotrexate Interactions Checker - Drugs.com
Methotrexate Interactions. There are 709 drugs known to interact with methotrexate, along with 5 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 140 are major, 555 are moderate, and 14 are minor.
Methotrexate Sodium: Package Insert / Prescribing Info - Drugs.com
2024年11月17日 · Methotrexate tablets can cause embryo-fetal toxicity, including fetal death. For non-neoplastic diseases, methotrexate tablets are contraindicated in pregnancy. For neoplastic diseases, advise patients of reproductive potential of the potential risk to a fetus and to use effective contraception (4, 5.1,8.1, 8.3). •
Methotrexate Injection: Package Insert / Prescribing Info
2024年11月10日 · Methotrexate Injection can cause embryo-fetal toxicity, including fetal death. Use in non-neoplastic diseases is contraindicated during pregnancy. Advise females and males of reproductive potential to use effective contraception during and after treatment with Methotrexate Injection. (4, 5.1, 8.1, 8.3) •
How do I know if methotrexate is working for rheumatoid arthritis?
2024年8月9日 · When methotrexate works it helps to slow joint damage and the progression of rheumatoid arthritis. In some people taking methotrexate, no or limited damage may be picked up on these tests (radiographic progression). However, methotrexate isn’t always able to prevent disease progression, especially in people with severe rheumatoid arthritis.
Methotrexate Monograph for Professionals - Drugs.com
2024年6月10日 · Delayed early methotrexate elimination and/or evidence of acute renal injury. Serum methotrexate ≥22.7 mcg/mL (50 µM) at 24 hours or ≥2.27 mcg/mL (5 µM) at 48 hours after administration, or a ≥100% increase in S cr concentration at 24 hours after methotrexate administration (e.g., an increase from 0.5 mg/dL to a concentration of ≥1 mg/dL)