RNA interference - Wikipedia
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression.
RNA Interference (RNAi) - National Center for Biotechnology Information
2017年11月9日 · RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is a conserved biological response to double-stranded RNA that mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
Molecular mechanisms of RNA interference - PMC - PubMed …
The three pathways of RNAi (miRNA, siRNA, piRNA) share a common mode of action: the minimal effector is an RNP complex comprising an Argonaute family protein bound to a single stranded ~20–30 nt RNA that grants specificity via base-pairing interactions with the gene target.
Basic Principles of RNA Interference: Nucleic Acid Types and In …
Since its discovery in 1989, RNA interference (RNAi) has become a widely used tool for the in vitro downregulation of specific gene expression in molecular biological research. This basically involves a complementary RNA that binds a target sequence to affect its transcription or translation process.
RNA interference | Explanation, Function, & Examples | Britannica
2024年10月18日 · RNA interference (RNAi), regulatory system occurring within eukaryotic cells (cells with a clearly defined nucleus) that controls the activity of genes. RNAi functions specifically to silence, or deactivate, genes.
What is RNAi - RNAi Biology | UMass Chan Medical School
The term RNA interference (RNAi) was coined to describe a cellular mechanism that uses the gene's own DNA sequence to turn it off, a process that researchers call silencing. In a wide variety of organisms, including animals, plants, and fungi, RNAi is …
RNAi mechanisms and applications - PMC - PubMed Central (PMC)
RNA interference (RNAi) is a regulatory mechanism of most eukaryotic cells that uses small double-stranded RNA (dsRNA) molecules as triggers to direct homology-dependent control of gene activity (Figure 1) (1).
RNA Interference (RNAi) - Steps, Applications, Mechanism
2024年5月16日 · RNA interference (RNAi) is a natural cellular process that regulates gene expression. It involves gene silencing or downregulation of specific genes by using small RNA molecules.
RNA Interference or RNAi - Microbiology Notes
2024年6月26日 · The process of RNAi or gene silencing is mediated by the endogenous RNAi pathway having foreign DNA or viral ds-RNA molecule. This pathway is divided into two steps: The cleavage of ds-RNA molecules into Si-RNA, mi-RNA by the action of DICER.
From guide to target: molecular insights into eukaryotic RNA ...
2015年1月7日 · RNA interference (RNAi) is a process by which small noncoding RNAs direct molecular machinery to silence gene expression. In this Review, Ipsaro and Joshua-Tor discuss the mechanisms and ...