Pathophysiology of Atherosclerosis - PMC
In this study, we aimed to review the mechanism of development of atherosclerosis, including endothelial dysfunction, fatty streak formation, fibrous plaque formation, and plaque rupture.
The Pathology of Atherosclerosis: Plaque Development and Plaque ...
Atherosclerosis is a disease of the arterial wall that occurs at susceptible sites in the major conduit arteries. It is initiated by lipid retention, oxidation, and modification, which provoke chronic inflammation, ultimately causing thrombosis or stenosis.
Atherosclerosis Pathology: Definition, Etiology, Epidemiology
Atherosclerosis pathology. Simplified scheme for classifying atherosclerotic lesions modified from the current American Heart Association (AHA) recommendations. The boxed areas represent the...
Atherosclerosis - StatPearls - NCBI Bookshelf
2020年9月10日 · Atherosclerosis is a chronic inflammatory disease in which there is a build up of plaques inside arteries. These plaques are principally composed of lipids that induce an inflammatory reaction causing turbulent flow with atherosclerotic cardiovascular disease (ASCVD) as …
Pathogenesis of atherosclerosis: A multifactorial process - PMC
Pathophysiological studies have unravelled the interactions of molecular and cellular elements involved in atherogenesis. The focus has shifted to the novel risk factors as well as characteristics and stability of atherosclerotic plaque; the genetic predisposition has further broadened the pathogenetic mechanisms.
Pathogenesis of atherosclerosis - UpToDate
2023年12月5日 · Atherosclerosis is a pathologic process that causes disease of the coronary, cerebral, and peripheral arteries and the aorta [1,2]. Forms of accelerated arteriopathies, such as restenosis following percutaneous coronary intervention with stenting and coronary transplant vasculopathy differ in pathogenesis and are discussed separately.
Pathophysiology of Atherosclerosis - PubMed
2022年3月20日 · This review focuses on the different stages of atherosclerosis development, ranging from endothelial dysfunction to plaque rupture. In addition, the post-transcriptional regulation and modulation of atheroma plaque by microRNAs and lncRNAs, the role of microbiota, and the importance of sex as a crucial risk factor in atherosclerosis are covered ...
Pathogenesis of Atherosclerosis | Hematology, ASH Education …
2005年1月1日 · The atherosclerotic process is characterized, in its earliest stages, by perturbations in endothelial function. Atherosclerosis is likely initiated when endothelial cells over-express adhesion molecules in response to turbulent …
Atherosclerosis: Recent developments - Cell Press
2022年5月12日 · Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the molecular, cellular, genetic, and environmental contributions to atherosclerosis, from both individual pathway and systems perspectives.
Atherosclerosis: Definition and pathogenesis - Kenhub
2023年7月24日 · Atherosclerosis is the thickening and loss of elasticity of arterial walls as a result of invasion and accumulation of white blood cells and proliferation of intimal smooth muscle cells that create a fibrofatty plaque.
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