Pathophysiology of Muscle Contractures in Cerebral Palsy
KEY POINTS. Muscle from patients with cerebral palsy shows functional deficits such as decreased force production and range of motion. Muscle is altered at a structural level, with decreased muscle body size, smaller-diameter fibers, and highly stretched sarcomeres (the force-producing unit of muscle).
Muscle contracture and passive mechanics in cerebral palsy
Contractures may occur because of an upper motor neuron lesion, such as stroke, head injury, or cerebral palsy (CP), or muscle disease, such as spinal muscular atrophy or muscular dystrophy. In such conditions, immobilization, muscle weakness, or paralysis with or without spasticity are key factors that lead to contracture development.
Joint Contractures and Cerebral Palsy - CP Family Network
Joint contractures and cerebral palsy are often synonymous. Learn the symptoms of joint contractures, how they're diagnosed, and available treatments.
Cerebral Palsy - National Institute of Neurological Disorders and Stroke
2024年7月19日 · Cerebral palsy (CP) refers to a group of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination. CP is caused by damage to or abnormalities inside the developing brain that disrupt the brain's ability to control movement and maintain posture and balance.
Skeletal Muscle in Cerebral Palsy: From Belly to Myofibril
2021年2月18日 · With respect to its musculoskeletal manifestations, cerebral palsy (CP) has been defined as a static encephalopathy, typified by muscle contractures (i.e., shortening) and bony deformities that are progressive with growth .
Muscle contracture and passive mechanics in cerebral palsy
2019年5月1日 · Skeletal muscle contractures represent the permanent shortening of a muscle-tendon unit, resulting in loss of elasticity and, in extreme cases, joint deformation. They may result from cerebral palsy, spinal cord injury, stroke, muscular …
Pathophysiology of muscle contractures in cerebral palsy
Patients with cerebral palsy present with a variety of adaptations to muscle structure and function. These pathophysiologic symptoms include functional deficits such as decreased force production and range of motion, in addition to changes in muscle structure such as …
Muscle in children with cerebral palsy: current evidence, …
2024年8月7日 · Cerebral palsy (CP) is associated with substantial deficits in muscle performance, as demonstrated by muscle weakness 1 and low power generation. 2 The major consequence is an inability or...
Cerebral palsy - Nature Reviews Disease Primers
2016年1月7日 · Contractures. Cerebral palsy has historically been called ‘short muscle disease’ owing to the prevalence of contractures 158,160. Shortening is at first ‘dynamic’ — secondary to hypertonia.
Sequence of flexion contracture development in the lower limb: a ...
2022年7月2日 · To prevent severe contractures and their impact on adjacent joints in children with cerebral palsy (CP), it is crucial to treat the reduced range of motion early and to understand the order by which contractures appear.