DNA Modifications: Function and Applications in Normal and …
In this review we summarize several important topics in relation to the role of DNA methylation in biology and human diseases. In the second section of the review we will discuss how DNA …
Genetic engineering - Wikipedia
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to …
Quantification and mapping of DNA modifications - PMC
The study of DNA modifications in individual cells will offer a new understanding of cell fate decisions, cell development, and disease progression. Mapping DNA modifications in a single …
Mapping epigenetic modifications by sequencing technologies
2023年9月1日 · Here, we summarize recent advances in epigenetic modification sequencing technologies, focusing on major histone, DNA, and RNA modifications in mammalian cells. …
DNAmod: the DNA modification database - Journal of …
2019年4月23日 · DNAmod is an open-source database (https://dnamod.hoffmanlab.org) that catalogues DNA modifications and provides a single source to learn about their properties. …
Genetic Engineering - National Human Genome Research Institute
3 天之前 · Genetic engineering (also called genetic modification) is a process that uses laboratory-based technologies to alter the DNA makeup of an organism. This may involve …
DNA modifications walk a fine line between epigenetics and
2023年2月22日 · In the study of DNA modifications, the disciplines of epigenetics and of DNA damage and repair have evolved separately. The lines are now blurred by the realization that …
DNA Modification, Cloning, Gene Splicing - Britannica
2024年10月28日 · Gene editing, based on a technology known as CRISPR-Cas9, allows researchers to customize a living organism’s genetic sequence by making very specific …
Prime editing: therapeutic advances and mechanistic insights
4 天之前 · A big part of the appeal of prime editing is its ability to precisely edit DNA without double stranded breaks, and to install any of the 12 possible single-nucleotide conversion …
Mapping the epigenetic modifications of DNA and RNA
2020年5月22日 · The interest in understanding the various biological functions of DNA and RNA modifications has lead to the cutting-edged fields of epigenomics and epitranscriptomics. …