A Diagnostic Approach to Patients with an IgM Monoclonal …
2014年9月17日 · Demonstration of IgM anti-myelin-associated glycoprotein (MAG) antibodies supports a causal relationship between IgM-MGUS and polyneuropathy but is not essential for the diagnosis. Because peripheral neuropathy can be caused by other processes that may co-exist with IgM-MGUS, the clinician is often faced with the dilemma of whether to assign ...
Anti-Human IgM Antibodies | Invitrogen - Thermo Fisher Scientific
Our Human IgM monoclonal, recombinant monoclonal, polyclonal and cocktail antibodies are developed in Mouse, Rabbit, Alpaca and Human. Find the Human IgM antibody that fits your needs. Choose from 1 of 72 Human IgM antibodies, which have been validated in experiments with 28 publications and 143 images featured in our data gallery.
Anti-Human IgM Antibodies | Invitrogen - 赛默飞世尔科技公司
Our Human IgM monoclonal, recombinant monoclonal, polyclonal and cocktail antibodies are developed in Mouse, Rabbit, Alpaca and Human. Find the Human IgM antibody that fits your needs. Choose from 1 of 72 Human IgM antibodies, which have been validated in experiments with 28 publications and 143 images featured in our data gallery.
Monoclonal Gammopathy–Associated Peripheral Neuropathy: …
2017年5月1日 · Monoclonal gammopathies comprise a spectrum of clonal plasma cell disorders that include monoclonal gammopathy of undetermined significance, multiple myeloma, and Waldenström macroglobulinemia. In this review, we outline the epidemiology, etiology, classification, diagnosis, and treatment of monoclonal …
Biochemistry, Immunoglobulin M - StatPearls - NCBI Bookshelf
2022年12月19日 · IgM is the first antibody secreted by the adaptive immune system in response to a foreign antigen. Monomeric IgM is a heterotetramer of approximately 180 kDa. However, the secreted form of IgM exists predominantly in a pentameric configuration with a molecular weight greater than 900 kDa.
Human IgM Monoclonal Antibody (4-B2) - Thermo Fisher Scientific
Huabio Anti-Human IgM Monoclonal (4-B2), Catalog # M1510-8. Tested in Western Blot (WB), Immunohistochemistry (Paraffin) (IHC (P)) and ELISA (ELISA) applications. This antibody reacts with Human samples. Supplied as 100 µL purified antibody (2 mg/mL).
IgM Monoclonal Antibody (II/41), FITC, eBioscience™
Mouse IgM is an immunoglobulin M antibody that is produced by B cells in response to an antigen. It is the first antibody produced during an immune response and is the largest immunoglobulin in the serum. Mouse IgM is composed of five heavy chains and five light chains, and it is involved in complement activation and agglutination of antigens.
Advances in the diagnosis, immunopathogenesis and therapies of IgM …
Polyneuropathy with immunoglobulin M (IgM) monoclonal gammopathy is the most common paraproteinemic neuropathy, comprising a clinicopathologically and immunologically distinct entity. The clinical spectrum spans from distal paresthesias and mild gait imbalance to more severe sensory ataxia, with falls and a varying degree of distal sensorimotor ...
IgM Antibody (R1/69) | SCBT - Santa Cruz Biotechnology
2024年7月11日 · IgM Antibody (R1/69) is an IgG1 κ mouse monoclonal IgM antibody that detects IgM of human origin by WB, IP, IF and IHC(P). IgM Antibody (R1/69) is available as the non-conjugated anti-IgM antibody form, as well as multiple conjugated forms of anti-IgM antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor ® conjugates.
Monoclonal antibody and intravenous immunoglobulin therapy for ... - Nature
The therapeutic efficacy of infliximab (a chimeric anti-TNF monoclonal antibody) or adalimumab (a fully human IgG 1 monoclonal antibody) in combination with methotrexate is now well...