Lactol - an overview | ScienceDirect Topics
2011年3月14日 · With lactol 71b in hand, the glycosylation was examined. Traditional methods for glycosylation of iridoid aglycones proceed via the acetylated lactol; however, in 2009 Krische 24 and coworkers reported the direct glycosylation of lactol 72 utilizing the trichloroacetimidate glycosyl donor 73 (Scheme 17, Equation 5). 33 As this had the potential to remove a synthetic operation, glycosylation of ...
Lactitol: Production, properties, and applications - ScienceDirect
2019年1月1日 · Lactitol is a multipurpose ingredient with various applications in the food, dairy, and pharmaceutical fields.
Comparing and taming the reactivity of HWE and Wittig reagents …
2011年10月5日 · In summary, lactol 1′/1″ is a model of very stable cyclic hemiacetalic forms of hydroxy-aldehydes. Their derivatives, with CH CH–EWG instead of CH O, show a similar strong tendency to form stable oxolanes (THF derivatives as very major products). If these are required, as happens in many cases, even in the total synthesis of several ...
A new synthetic approach to the lactol moiety of halichoblelide
2011年7月22日 · A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from commercially available (R)-3-butyn-2-ol. The key step is the hydroboration of a chiral protected 1,2-butadien-3-ol and its addition to furfural.
Lactone - an overview | ScienceDirect Topics
Lactone Microorganism Substrate Odor and taste; Gamma-hexalactone: Sweet, coconut, cream, herbaceous, hay, woody: Gamma-heptalactone
Facile conversion of lactols to lactones using IBX
2004年1月5日 · The mechanism of formation of the lactones may be described in a manner analogous to that described for the conversion of alcohols to aldehydes or ketones. 9 Accordingly, the attack of the lactol should furnish the intermediate in Scheme 2, which may decompose to the lactone and IBA (iodosobenzoic acid), the reduction product of IBX.
Lactones: Classification, synthesis, biological activities, and ...
2021年3月26日 · Decalactones, or nonanolides, are the best-known natural medium-sized lactones (Fig. 7) and show a variety of biological properties.
Wittig reaction with partially protected sugar lactol derivatives ...
2004年12月13日 · Thus, the lactol 14 reacted with Ph 3 P:CHCO 2 Me in refluxing acetonitrile to form an intermediate enoate (not shown in the Scheme), which then underwent a spontaneous Michael ring closure, affording a mixture of α- and β-C-glycosides 15 20 and 16 21 in a …
Isolation, identification, and metabolism of (23S,25R)-25 ...
1984年1月25日 · THE JOURNAL OF BIOLOGICAL CHEMISTRY 0 1984 by The American Society of Biological Chemists, Inc. Vol. 259, No. 2, Issue of January 25, pp. W-889, 1984 Printed in U S A Isolation, Identification, and Metabolism of (23S,25R)-25- Hydroxyvitamin D3 26,23-Lactol A BIOSYNTHETIC PRECURSOR OF (23S,25R)-25-HYDROXYVITAMIN D3 26,23-LACTONE* (Received for publication, March 25, 1983) Sachiko Yamada, Keiko ...
Cell-free biocatalysis coupled with photo-catalysis and electro ...
2024年9月1日 · This hybrid system achieved the synthesis of 752 ± 65 mg L −1 C6 lactol at a synthesis rate of 5.7 mmol L −1 day −1 (Fig. 7 a). In addition to prodrugs, Ma et al. have successfully created an artificial route ASAP for starch synthesis using electrical energy and multi-enzyme catalysis in cell-free system.