Losartan: Uses, Interactions, Mechanism of Action | DrugBank ...
Losartan is an angiotensin II receptor blocker used to treat hypertension, diabetic nephropathy, and to reduce the risk of stroke. 1,3,4 Losartan has a long duration of action as it is given once daily. 3,4 Patients taking losartan should be regularly monitored for hypotension, renal function, and potassium levels. 3,4
How Does Losartan Work? Its Mechanism of Action Explained ...
2024年1月22日 · Losartan’s mechanism of action is complex. It works by blocking the actions of angiotensin II, a hormone that increases blood pressure. It does this by blocking it from attaching to angiotensin II receptors, which also helps prevent damage to the kidneys and heart.
Losartan: Uses, Dosage, Side Effects, Warnings - Drugs.com
2024年2月29日 · Losartan belongs to a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.
Losartan - StatPearls - NCBI Bookshelf
2024年2月26日 · The onset of action of losartan is 6 hours and lasts approximately 24 hours. Distribution: Losartan's plasma protein binding (PPB) is high, with approximately 98.7% of losartan bound to plasma proteins; the active metabolite E-3174 has a …
Losartan: Dosage, Mechanism/Onset of Action, Half-Life ...
2020年2月17日 · Includes Losartan indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.
Losartan (oral route) - Mayo Clinic
Losartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, losartan relaxes the blood vessels. A lower blood pressure will increase the supply of the blood and oxygen to the heart.
Losartan - Wikipedia
Losartan is a selective, competitive angiotensin II receptor type 1 (AT 1) antagonist, reducing the end organ responses to angiotensin II. Losartan administration results in a decrease in total peripheral resistance (afterload) and cardiac venous return (preload).
Losartan: 7 things you should know - Drugs.com
2023年8月29日 · Losartan works by blocking the effect of angiotensin II, a hormone that causes blood vessels to narrow (constrict) increasing blood pressure. Blocking angiotensin II widens (dilates) blood vessels which lowers blood pressure. Losartan also increases the excretion of certain salts from the kidney.
Losartan (Cozaar) - Uses, Side Effects, and More - WebMD
2024年5月21日 · How does losartan work (mechanism of action)? Losartan blocks receptors in your body that normally bind to a hormone called angiotensin II. When angiotensin II binds to these receptors, it...
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