Malate dehydrogenase - Wikipedia
Malate dehydrogenase (EC 1.1.1.37) (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD + to NADH. This reaction is part of many …
Catalytic mechanism and kinetics of malate dehydrogenase
2024年10月3日 · Malate dehydrogenase (MDH, EC 1.1.1.37) catalyzes the reversible conversion of L-malate ((S)-malate) to oxaloacetate, accompanied by the conversion of NAD + to NADH + …
Catalytic mechanism and kinetics of malate dehydrogenase
2024年10月3日 · This review describes the reaction mechanism for MDH and the effects of mutations in and around the active site on catalytic activity and substrate specificity, with a …
Determination of the Catalytic Mechanism for Mitochondrial Malate ...
Malate dehydrogenase (MDH, EC: 1.1.1.37) reversibly catalyzes the oxidation of L-malate (MAL) to oxaloacetate (OAA), reducing NAD to NADH in the process. In eukaryotes this enzyme is …
Malate dehydrogenase: Mechanism - University of …
Mechanism: There are two plausible reaction pathways in the conversion of malate to oxaloacetate. The reaction transfers a hydride molecule and requires a coenzyme (NAD +). …
Malate Dehydrogenase - an overview | ScienceDirect Topics
Malate dehydrogenase (EC 1.1.1.37) catalyzes the reversible conversion of oxaloacetate to l-malate with the participation of NAD(H). Malate dehydrogenase is a multimeric enzyme …
Malate dehydrogenases--structure and function - PubMed
They are homodimeric molecules in most organisms, including all eukaryots and the most bacterial species. The enzymes share a common catalytic mechanism and their kinetic …
Malate dehydrogenase: distribution, function and properties
Malate dehydrogenase (MDH) (EC 1.1.1.37) catalyzes the conversion of oxaloacetate and malate. This reaction is important in cellular metabolism, and it is coupled with easily detectable …
mechanism for the malate dehydrogenase reaction has been postulated and a schematic illustration of the transition state of the enzyme is presented.
Function, kinetic properties, crystallization, and regulation of ...
Malate dehydrogenase (MDH) is an enzyme widely distributed among living organisms and is a key protein in the central oxidative pathway. It catalyzes the interconversion between malate …