GTPase - Wikipedia
GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP). [1] . The GTP binding …
Small GTPase - Wikipedia
Small GTPases (EC 3.6.5.2), also known as small G-proteins, are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP).
Small GTPases: Structure, biological function and its
2019年1月1日 · Small GTPase is a kind of GTP-binding protein commonly found in eukaryotic cells. It plays an important role in cytoskeletal reorganization, cell polarity, cell cycle …
G-Proteins and Their Molecular Targets - Neuroscience - NCBI …
The second class of GTP-binding proteins are monomeric G-proteins (also called small G-proteins). These monomeric GTPases also relay signals from activated cell surface receptors …
Small GTPases - Latest research and news | Nature
2024年12月4日 · Small GTPases are a large family of monomeric proteins that bind and hydrolyse GTP to GDP. Small GTPases activate downstream effectors when bound to GTP.
Regulation of small GTPases by GEFs, GAPs, and GDIs
The GTPase switch is turned on by GEFs, which stimulate dissociation of the tightly bound GDP, and turned off by GAPs, which accelerate the intrinsically sluggish hydrolysis of GTP. For Ras, …
Small Monomeric GTPases | GTPases | Tocris Bioscience
The RAS family of small monomeric GTPases regulate gene expression, cell proliferation, differentiation and cell survival, and are commonly mutated in cancers. This blog post …
Small GTPases - PubMed
2018年8月16日 · Small GTPases are tightly regulated molecular switches that make binary on/off decisions through controlled loading of GTP (activation) and hydrolysis of GTP to GDP …
The Small GTPases in Fungal Signaling Conservation and Function
2021年4月28日 · Monomeric GTPases, which belong to the Ras superfamily, are small proteins involved in many biological processes. They are fine-tuned regulated by guanine nucleotide …
Small Monomeric GTPases - Tocris Bioscience
The RAS family of small monomeric GTPases regulate gene expression, cell proliferation, differentiation and cell survival, and are commonly mutated in cancers. This blog post …
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