Multiple drug resistance - Wikipedia
Multiple drug resistance (MDR), multidrug resistance or multiresistance is antimicrobial resistance shown by a species of microorganism to at least one antimicrobial drug in three or more antimicrobial categories. [1] Antimicrobial categories are classifications of antimicrobial agents based on their mode of action and specific to target ...
多药耐药性 - 百度百科
肿瘤耐药的产生可分为原发性耐药和获得性耐药，根据肿瘤细胞的耐药特点，其获得性耐药可分为原药耐药（primary drug resistance，PDR）和多药耐药（multidrug resistance，MDR）两大类。 PDR 是指仅对诱导药物产生交叉耐药；而 MDR 是指肿瘤细胞对一种抗肿瘤药物产生抗药性的同时，对结构和作用机制不同的抗肿瘤药物产生交叉耐药性，又称多向性耐药（pleiotropic drug resistance）。 MDR 是肿瘤化疗失败的主要原因，也是困扰肿瘤治疗的一大难题 [2]。 因此， …
Multidrug Resistance (MDR): A Widespread Phenomenon in …
Multidrug resistance is a leading concern in public health. It describes a complex phenotype whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic compounds, many of which are anticancer agents.
Multidrug Resistance (MDR): A Widespread Phenomenon in
2022年1月18日 · Multidrug resistance is a leading concern in public health. It describes a complex phenotype whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic compounds, many of which are anticancer agents. Multidrug resistance may be also related to antimicrobial drugs, an …
Multidrug Resistance: An Emerging Crisis - PMC - PubMed …
Multidrug resistance (MDR) is defined as insensitivity or resistance of a microorganism to the administered antimicrobial medicines (which are structurally unrelated and have different molecular targets) despite earlier sensitivity to it [1, 2].
多重性耐药菌 - 百度百科
多重性耐药菌(multiple resistant bacteria)是指有多重耐药性的病原菌。 Multiresistance可以翻译成多药耐药性、多重耐药性、其定义为一种微生物对三类或三类以上抗生素同时耐药，而不是同一类三种。
多重耐药性 - 百度百科
基因盒为附着在一个小的识别部位的一个耐药基因组成，数个基因盒可以被包装成一个多基因盒阵列，并依次被整合进入一个易于快速流动的较大的DNA单位，称为整合子。 整合子含有一种整合酶基因，可以将基因盒插入到整合子的特异部位。 这样一个转座子-整合子-多重耐药基因盒阵列的系统允许多重耐药性在细菌内的基因元素之间特别迅速而又有效地进行转移，常造成耐药菌特别是对多种抗菌药物都耐药的多重耐药性细菌感染的广泛扩散。
多重耐药与泛耐药有何根本区别 - biomart.cn
2015年1月4日 · 多重耐药性(multiple resistance, MDR) 系指同时对多种常用抗微生物药物发生的耐药性, 主要机制是外排膜泵基因突变, 其次是外膜渗透性的改变和产生超广谱酶。
Multiple Drug Resistance - an overview | ScienceDirect Topics
Multidrug resistance (MDR) is defined as resistance of tumor cells to the cytotoxic action of multiple structurally dissimilar and functionally divergent drugs commonly used in chemotherapy. From: Bioorganic & Medicinal Chemistry, 2008
Multiple Drug Resistance - an overview | ScienceDirect Topics
Multiple drug resistance (MDR) refers to the cancer cells resistant to a wide variety of mechanistically and structurally diverse anti-tumor drugs, which is a significant challenge in the failure of cancer chemotherapy [19].