Chloroquine for Coronavirus: Can It Treat People with COVID-19? - WebMD
2023年1月4日 · Can chloroquine treat coronavirus? There’s some very early science, but not a lot, to back the idea that this antimalarial drug might have promise against COVID-19. Learn more.
Efficacy and safety of hydroxychloroquine as pre-and post …
2021年7月2日 · Hydroxychloroquine (HCQ) has been evaluated as a potential repurposing drug to prevent and treat SARS-CoV-2 infection. We searched PubMed, Embase, and Web of Science databases with no language restrictions for published meta-analyses synthesizing evidence on the efficacy and safety of HCQ as prophylaxis and treatment of COVID-19.
An Update: Is hydroxychloroquine effective for COVID-19? - Drugs.com
2024年8月26日 · Hydroxychloroquine, an FDA-approved prescription drug used for malaria, rheumatoid arthritis and lupus erythematosus, has been suggested as a possible treatment or preventive for COVID-19 based on demonstrated antiviral or immune system activity.
Hydroxychloroquine for the Prevention of Covid-19 — Searching …
2020年6月3日 · Adults who described a high-risk or moderate-risk exposure to someone with Covid-19 in their household or an occupational setting were provided hydroxychloroquine or placebo (by mail) within 4...
Chloroquine and hydroxychloroquine during the COVID-19 …
Widespread administration of chloroquine or hydroxychloroquine, either alone or in combination with azithromycin, among COVID-19 patients, has been associated with increased mortality due to adverse effects, including QT prolongation.
Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19
2020年10月8日 · In this randomized, controlled, open-label platform trial comparing a range of possible treatments with usual care in patients hospitalized with Covid-19, we randomly assigned 1561 patients to...
Hydroxychloroquine for the treatment of severe respiratory …
Our objective was to estimate whether treatment with 400 mg/day of Hydroxychloroquine for 10 days reduces in-hospital mortality in subjects with severe respiratory disease due to COVID-19 compared with placebo.
Chloroquine in fighting COVID-19: good, bad, or both? - PMC
Chloroquine can fight coronavirus infection in several different ways: 1) Increasing the endosomal pH. Coronaviruses are enveloped, positive-stranded RNA viruses. After endocytosis, these viruses deliver their genomes into host cells through low-pH endosomes. Chloroquine is a di-protonic weak base.
Chloroquine to fight COVID-19: A consideration of mechanisms …
2020年9月9日 · Chloroquine (CQ) and hydroxychloroquine (HCQ) were widely adopted in treating COVID-19, but the results were contradictive. CQ/HCQ have been used to prevent and treat malaria and are efficacious anti-inflammatory agents …
New insights on the antiviral effects of chloroquine against ...
Recently, the China National Center for Biotechnology Development indicated that chloroquine is one of the three drugs with a promising profile against the new SARS-CoV-2 coronavirus that causes COVID-19.
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