Palonosetron (intravenous route) - Mayo Clinic
Palonosetron injection is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy). It is also used to prevent nausea and vomiting for up to 24 hours that may occur after surgery. Palonosetron works by blocking the signals to …
Palonosetron injection Uses, Side Effects & Warnings - Drugs.com
2024年4月23日 · Palonosetron is used in adults to prevent nausea and vomiting caused by surgery, or by receiving medicine to treat cancer (chemotherapy). Palonosetron is used in children as young as 1 month old only to prevent nausea and vomiting caused by cancer medicine. Palonosetron may also be used for purposes not listed in this medication guide.
Palonosetron HCl Injection is indicated for prevention of postoperative nausea and vomiting (PONV) for up to 24 hours following surgery. Efficacy beyond 24 hours has not been demonstrated.
Palonosetron - Uses, Side Effects, and More - WebMD
2024年7月3日 · What is palonosetron used for? Palonosetron is commonly used to prevent nausea and vomiting that can happen when using medicines for cancer (chemotherapy) and after surgery. Palonosetron may also...
Palonosetron Injection: MedlinePlus Drug Information
Palonosetron injection comes as a solution (liquid) to be injected intravenously (into a vein) by a healthcare provider in a hospital or clinic. When palonosetron is used to prevent nausea and vomiting caused by chemotherapy, it is usually given as a single dose about 30 minutes before the start of chemotherapy.
Palonosetron Dosage Guide + Max Dose, Adjustments - Drugs.com
2024年4月23日 · 1 month to younger than 17 years: 20 mcg/kg via IV infusion over 15 seconds ONCE 30 minutes before the start of chemotherapy. Maximum dose: 1.5 mg; 17 years and older: 0.25 mg via IV infusion over 30 seconds ONCE 30 minutes before the …
Palonosetron: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月10日 · IV: Flush IV line with NS prior to and following administration. Prevention of chemotherapy-induced nausea and vomiting: Infuse over 30 seconds, beginning ~30 minutes prior to the start of chemotherapy
Phase III study of palonosetron (PALO) given as 30-min IV infusion (IV …
2017年11月14日 · Oral NEPA is approved for acute and delayed CINV prophylaxis after moderately (MEC) and HEC. This study was conducted in support of the NEPA IV formulation (0.25 mg PALO + 235 mg fosnetupitant) administered as a …
Aloxi, Posfrea (palonosetron) dosing, indications, interactions ...
Indicated for prevention of acute N/V associated with moderately or highly emetogenic chemotherapeutic agents; also for delayed N/V associated moderately emetogenic chemotherapeutic agents. 0.25 mg...
Palonosetron (PALO), administered orally or intravenously (IV), …
2008年5月20日 · Three oral doses of PALO 0.25, 0.50 or 0.75 mg were shown to be clinically comparable to the approved dose of 0.25 mg IV for the prevention of CINV in a recent, multinational, multicenter, double-blind, phase 3 dose ranging study of 651 patients receiving moderately emetogenic chemotherapy (including AC-based regimens) [Grunberg et al, ECCO ...