Platinum-Based Chemotherapy: Uses, Effectiveness, Side Effects
2022年11月2日 · Platinum-based chemotherapy drugs are used to treat many types of cancer, particularly those that are platinum-sensitive. Learn more.
Platinum-based antineoplastic - Wikipedia
Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. Their active moieties are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer.
Platinum-based chemotherapy: What to know - Medical News Today
2023年8月30日 · Platinum-based chemotherapy is a type of cancer treatment that involves drugs containing platinum ion compounds. Doctors commonly use these drugs to treat various types of...
Platinum drugs in the treatment of non-small-cell lung cancer
Randomised clinical studies and meta-analyses of the literature have confirmed the beneficial survival effect of platinum-based chemotherapy. Cisplatin and carboplatin have been successfully used with other drugs in a wide variety of well-established two-drug combinations while three-drug combinations are still under investigation.
Platinum-based drugs for cancer therapy and anti-tumor ...
2022年2月7日 · Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such as lack of selectivity, high systemic toxicity, and drug resistance, seriously limit their clinical application.
The rediscovery of platinum-based cancer therapy - Nature
2020年10月30日 · Nature Reviews Cancer - Platinum chemotherapy agents remain among the most widely used anticancer drugs, but there is still room to maximize their efficacy. This Review discusses newer findings...
Reevaluating the role of platinum-based chemotherapy in the ...
2024年8月21日 · Introduction. Urothelial carcinoma (UC) is a chemotherapy-sensitive tumor, and platinum-based chemotherapy has been the cornerstone of first-line (1L) treatment for advanced UC for decades. 1-4 The antitumor mechanisms of platinum-based chemotherapy include both direct cytotoxicity (DNA damage, mitochondrial damage, and oxidative stress) and potential …