Ran (protein) - Wikipedia
Ran's intrinsic GTPase-activity is activated through interaction with Ran GTPase activating protein (RanGAP), facilitated by complex formation with Ran-binding protein (RanBP). GTPase …
What are Ran GTPases? - National University of Singapore
2023年11月30日 · The Ran (Ran-related or Ras-like nuclear) protein is the single member of the Ran subfamily, and the most abundant small GTPase in the cell. Like the other small …
Ran GTPase: A Key Player in Tumor Progression and Metastasis
2020年5月26日 · Ran regulates nucleo-cytoplasmic transport of molecules through the nuclear pore complex and controls cell cycle progression through the regulation of microtubule …
Ran GTPase: A Key Player in Tumor Progression and Metastasis
In the present review, we highlight the prognostic value of Ran GTPase in cancer patients and focus on its role in the tumorigenic process. In particular, we examine the involvement of Ran …
Ran GTPase and Its Importance in Cellular Signaling and …
Ran is a member of the Ras superfamily of proteins, which primarily regulates nucleocytoplasmic trafficking and mediates mitosis by regulating spindle formation and nuclear envelope (NE) …
Coordination of Cell Cycle Events by Ran GTPase
Several elegant studies indicate that the small GTPase called Ras-related nuclear protein (Ran) is a central regulator of several cell cycle events. In the 1990s, scientists first...
Ran GTPase: a master regulator of nuclear structure and function …
2001年9月1日 · Ran is an abundant GTPase that is highly conserved in eukaryotic cells and has been implicated in many aspects of nuclear structure and function, especially determining the …
The Ran GTPase: Theme and Variations - ScienceDirect
2002年7月23日 · Our emergent understanding of Ran suggests that it plays a central role in spatial and temporal organization of the vertebrate cell. Ran is a Ras-related GTPase that acts …
Ran promotes membrane targeting and stabilization of RhoA to ...
2019年6月17日 · We have demonstrated that the small GTPAse Ran (Ras-related nuclear protein) is strongly associated with EOC progression, poor overall survival, and a high risk of …
The Ran GTPase as a marker of chromosome position in spindle …
2002年7月1日 · The small GTPase Ran is a key regulator of nucleocytoplasmic transport during interphase. The asymmetric distribution of the GTP-bound form of Ran across the nuclear …