Pathology Outlines - Retinoblastoma
2021年11月2日 · Retinoblastoma is the most common intraocular malignancy in children characterized by hyperchromatic small round blue cells with scant cytoplasm arranged in sheets, nests and trabeculae Prognosis dependent on many factors; histopathological evaluation determines metastatic risk, including tumor invasion into anterior chamber, significant ...
Histopathological Characteristics and Classification for Prognostic ...
2019年9月29日 · Retinoblastoma (RB) is the most common intraocular tumor in children. It arises from the nuclear layer of the retina, with different growth patterns: endophytic, exophytic, and mixed. Retinoblastoma also has characteristic histopathological appearance with areas of viable tumor, necrosis, and calcifications.
Review of Retinoblastoma - American Academy of Ophthalmology
2016年4月28日 · Retinoblastoma is a primitive neuroectodermal intraocular malignancy that affects young children. It is the most common primary intraocular malignancy in children, frequently presenting with leukocoria. Multiple estimates of the incidence of retinoblastoma in various populations and countries have been published.
Retinoblastoma - Libre Pathology
Endophytic - grow into the vitreous cavity. Exophytic - grow toward choroid. Mixed - components of endophytic and exophytic. Note: Tumour is extremely friable. Retinoblastoma (radiopaedia.org/AFIP). Features: Scant cytoplasm. Flexner-Wintersteiner rosette - key feature. Rosette with empty centre (donut hole). [2] +/-Homer-Wright rosette. [3]
Histopathology of Retinoblastoma - SpringerLink
Retinoblastoma is a primitive neuroectodermal tumor of the retina, which in view of its histopathologic as well as clinical characteristics has to be regarded as a specific clinical entity (Becker and Hinton 1983).
Update on pathology of retinoblastoma - PMC
Histopathological high-risk features of retinoblastoma are predictive of metastasis or local recurrence. The focus of this update is to emphasize the recent advances in pathology, various molecular key pathways and genome wide approaches for newer potential therapeutic future targets associated with retinoblastoma tumor biology.
Standard reporting of high-risk histopathology features in retinoblastoma
2018年6月3日 · The RCPath dataset for retinoblastoma records whether tumour is present in specific structures. Presence of tumour in any of these structures is considered a histological high-risk feature (HHRF). Retinoblastoma specimens with HHRFs indicate that the patient is at higher risk for metastasis (tumour spread) than a patient whose specimen does not ...
Retinoblastoma: Clinical and histopathologic features
1982年2月1日 · Retinoblastoma, the ocular tumor of childhood, is unusual in its genetic implications, the frequency of occurrence of second primary tumors, the association of a 13q14 chromosome deletion, and the high incidence of spontaneous regression.
Retinoblastoma - Radiology Key
2016年6月19日 · Retinoblastoma (RB) is the most common malignant intraocular tumor of childhood. The tumor is of neuroepithelial origin and arises from the nucleated layers of one or both eyes ( 1 ). RB consists of undifferentiated small …
Retinoblastoma is a primitive neuroectodermal tumor of the retina, which in view of its histo pathologic as well as clinical characteristics has to be regarded as a specific clinical entity (BECKER and HINTON 1983). The term "retinoblastoma" dates back …