Promoter (genetics) - Wikipedia
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein (mRNA), or can have a function in and of itself, such as tRNA or rRNA.
11: Transcription: Promoters, terminators and mRNA
2023年6月20日 · The core promoter covers the start site of transcription, from about ‑40 to about +30. The promoter also contains an upstream control element located about 70 bp further 5', extending from ‑170 to ‑110.
Promoter - National Human Genome Research Institute
1 天前 · A promoter, as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and transcription factors) bind to initiate transcription of that gene. The resulting transcription produces an RNA molecule (such as mRNA).
Promoters - Addgene
A promoter is a region of DNA where transcription of a gene is initiated. Promoters are a vital component of expression vectors because they control the binding of RNA polymerase to DNA. RNA polymerase transcribes DNA to mRNA which is ultimately translated into a functional protein.
Transcriptional gene expression: Activators and repressors
In prokaryotes, activators can stabilize the transcription machinery at a weak promoter by binding both DNA and either polymerase or sigma factor. Repressors commonly bind to DNA and block access of the RNA polymerase holoenzyme to the promoter, preventing transcription. This is often accomplished via the simple mechanism of taking up space!
Eukaryotic core promoters and the functional basis of transcription ...
The term ‘promoters’ refers to sequences at gene starts, which can autonomously drive high levels of productive transcription. Promoters comprise in close proximity core promoters and supporting activating sequences, which are called proximal promoters or proximal enhancers (discussed in REFS 198, 210).
Eukaryotic core promoters and the functional basis of transcription ...
2018年6月26日 · RNA polymerase II (Pol II) core promoters are specialized DNA sequences at transcription start sites of protein-coding and non-coding genes that support the assembly of the...
7.5B: The Promoter and the Transcription Machinery
2024年11月23日 · The purpose of the promoter is to bind transcription factors that control the initiation of transcription. The promoter region can be short or quite long; the longer the promoter is, the more available space for proteins to bind.
Sequence basis of transcription initiation in the human genome
Furthermore, we explain the sequence basis of bidirectional transcription at promoters, identify the links between promoter sequence and gene expression variation across cell types, and explore the conservation of sequence determinants of transcription initiation across mammalian species.
16.4.1: The Promoter and the Transcription Machinery
2021年12月16日 · The purpose of the promoter is to bind transcription factors that control the initiation of transcription. The promoter region can be short or quite long; the longer the promoter is, the more available space for proteins to bind.