Parapoxvirus - Wikipedia
Parapoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Chordopoxvirinae. [1] Like all members of the family Poxviridae, they are oval, relatively large, double-stranded DNA viruses. Parapoxviruses have a unique spiral coat that distinguishes them from other poxviruses.
Parapoxvirus - an overview | ScienceDirect Topics
Poxviruses belong to the family Poxviridae. Those which infect humans are found among four genera (Orthopoxvirus, Parapoxvirus, Molluscipoxvirus and Yatapoxvirus) within the Chordopoxvirinae subfamily (Table 28.2-1). The majority of poxvirus infections in humans are zoonoses, with only variola and molluscum contagiosum viruses being uniquely ...
Parapoxvirus - an overview | ScienceDirect Topics
Parapoxvirus is the organism responsible for orf, a zoonotic infection that is transmitted to humans via contact with infected animals, most commonly sheep. It is thus most frequently seen in those with professional exposure, such as butchers, sheep shearers, and veterinarians.
Parapoxviruses: Background, Pathophysiology, Epidemiology - Medscape
2023年11月7日 · Parapoxvirus infections manifest as pathologic lesions on the animal's oral mucosa (eg, lips, nostrils, eyes) or the moist hairless areas of the skin (eg, udders, groin). The...
Immunomodulatory Strategies for Parapoxvirus: Current Status …
2021年11月17日 · Parapoxvirus (ORFV) is well recognized for its ability to withstand numerous challenges to the host-triggered immune response. ORFV is able to partially circumvent the host immune response because upon acute infection of the mucocutaneous boundaries of the epidermis, the virus immediately releases multiple virulence proteins that subvert host ...
Parapoxvirus - an overview | ScienceDirect Topics
Parapoxviruses (PPVs) are epitheliotropic viruses found worldwide. The individual viruses generally exhibit a narrow host range and infect via scarified or damaged skin and give rise to pustular lesions of the skin and occasionally the buccal mucosa. These lesions are associated with low mortality and high morbidity.
Genus Parapoxvirus - PMC - National Center for Biotechnology …
Several genes of parapoxviruses are unique to this genus and encode factors that target inflammation, the innate immune responses and the development of acquired immunity. These factors include a homologue of mammalian interleukin (IL)-10, a chemokine binding protein and a granulocyte-macrophage colony stimulating factor /IL-2 binding protein.
Human Infection with Orf Virus and Description of Its Whole …
Parapoxvirus is a genus of double-stranded DNA viruses (family Poxviridae) that contains 4 virus species: orf virus, bovine papular stomatitis virus, parapoxvirus of red deer, and pseudocowpoxvirus. Recently, a complete genome from a gray seal infected by a parapoxvirus was reported and constituted a putative novel virus in this genus ( 1 ).
Genus: Parapoxvirus | ICTV
Members of the genus Parapoxvirus generally infect ungulates with disease apparent in livestock species and wildlife. Exceptions are members of the species Grey sealpox virus. Disease is found world-wide wherever livestock species are farmed. It is generally self-limiting and normally manifests as a localised erythematous pustular dermatitis.
Parapoxviruses: from the lesion to the viral genome - PubMed
Viruses of the genus parapoxvirus from the family poxviridae cause widespread but localized diseases of small and large ruminants. The economically most important disease is contagious pustular dermatitis or contagious ecthyma among sheep and goats, often simply called orf.