RhoA drives actin compaction to restrict axon regeneration and ...
2021年11月3日 · In response to extracellular inhibitors, neuronal RhoA restricts axon regeneration by activating myosin II to compact actin and, thereby, restrain microtubule protrusion. …
In response to extracellular inhibitors, neuronal RhoA restricts axon regeneration by activating myosin II to compact actin and, thereby, restrain microtubule protrusion. However, astrocytic …
Untangling the role of RhoA in the heart: protective effect and ...
2024年8月9日 · Activation of RhoA induces polymerization of G-actin to form F-actin filaments, freeing MRTF-A to translocate to the nucleus, and this triggers activation of SRF target genes …
Pulses of RhoA signaling stimulate actin polymerization and flow …
2024年1月22日 · Positive and negative feedbacks cause RhoA and myosin II activities to pulse. These pulses of RhoA signaling stimulate actin polymerization at the tip of the protrusions and …
RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to ...
2016年12月19日 · The small GTPase RhoA regulates the actin cytoskeleton to affect multiple cellular processes including endocytosis, migration and adhesion. RhoA activity is tightly …
Regulation of RhoA GTPase and various transcription factors in the RhoA ...
As the role of RhoA in regulating actin-filament formation and myosin-actin interaction has been well described, in this review we focus on the transcriptional activity of RhoA and also the …
The DIAPH3 linker specifies a β-actin network that maintains RhoA …
2024年6月19日 · β-actin maintains RhoA at the furrow. The localization of RhoA-GTP, the active form of RhoA, to the future site of furrow ingression, is considered a crucial early event driving …
Patterning of the cell cortex by Rho GTPases
2024年1月3日 · The Rho GTPases — RHOA, RAC1 and CDC42 — are small GTP binding proteins that regulate basic biological processes such as cell locomotion, cell division and …
RhoA, a Rho GTPase and regulator of actin-based ... - Cytoskeleton
RhoA is a 22 kDa small GTPase, a member of the Ras super-family and Rho sub-family of GTPases, that upon activation by a guanine nucleotide exchange factor (GEF), is essential in …
RhoA drives actin compaction to restrict axon regeneration and ...
2021年11月3日 · In response to extracellular inhibitors, neuronal RhoA restricts axon regeneration by activating myosin II to compact actin and, thereby, restrain microtubule protrusion. …